Huu-Hung NguyenXuan-Hao BuiThi-Minh-Dinh TranJirapast SichaemThi-Kim-Dung LeNgoc-Hong NguyenThuc-Huy Duong2022-11-092022-11-092021https://repository.vlu.edu.vn/handle/123456789/110010.1080/10286020.2021.1953481Phytochemical investigation on the leaves of Combretum quadrangulare growing in Vietnam afforded a new trinorcycloartane triterpenoid, norquandrangularic acid D (1), along with three known compounds, betulinic acid (2), luteolin (3), and apigenin (4). Their structures were elucidated using spectroscopic methods and comparison was made with reports in the literature. Compounds 1 and 3 were evaluated for α-glucosidase inhibition. Compound 3 showed significant activity, with an IC50 value of 11.39 µM, (acarbose, used as a positive control, had an IC50 of 367 µM).en-USjournal-article