Hoang-Vinh-Truong PhanThuc-Huy DuongDuc-Dung PhamHoang-Anh PhamVan-Kieu NguyenThi-Phuong NguyenHuu-Hung NguyenNgoc-Hong NguyenPornpat Sam-angKiettipum PhontreeJirapast Sichaem2022-11-032022-11-032020https://repository.vlu.edu.vn/handle/123456789/82810.1080/14786419.2020.1758095were designed, synthesised and evaluated for their a-glucosidase inhibitory and cytotoxic activities. Among synthetic derivatives, lupeol analogues 2b and 2e containing a benzylidene chain exhibited the best activity against a-glucosidase and superior to the positive agent with the IC50 values of 29.4 ± 1.33 and 20.1 ± 0.91 lM, respectively. Lupeol analogues 2d and 3a showed weak cytotoxicity against K562 cell line with the IC50 values of 76.6 ± 2.40 and 94.4 ± 1.51 lM, respectively.en-USRetrieving data. Wait a few seconds and try to cut or copy again.journal-article